Тромбоз венозных синусов головного мозга и кровоизлияние в ткань головного мозга у пациента с лимфобластной лимфомой

Пациенты с лимфобластными лимфомами успешно лечатся по протоколам, разработанным немецкой группой BFM (Berlin-Frankfurt-Münster). Редким осложнением терапии лимфобластных лимфом является тромбоз венозного синуса. Представлен клинический случай развития сочетанного тромбогеморрагического состояния у мальчика 12 лет с лимфобластной лимфомой. Ребенку проводили заместительную терапию фактором протромбинового комплекса, препаратом антитромбина III и антикоагулянтную терапию высокомолекулярным гепарином с переходом на низкомолекулярный гепарин. Через 5 мес антикоагулянтной терапии у ребенка зарегистрирована полная реканализация пораженных синусов.

дети, лимфобластная лимфома, геморрагический инсульт, тромбоз венозного синуса, L-аспарагиназа, children, lymphoblastic lymphoma, hemorrhagic stroke, venous sinus thrombosis, L-asparaginase

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