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Технологии инактивации патогенов и качество концентратов тромбоцитов (обзор литературы)

https://doi.org/10.24287/1726-1708-2016-15-2-27-31

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Аннотация

Переливание концентратов тромбоцитов (КТ) является практически единственным быстрым и универсальным способом коррекции тромбоцитарной функции при широком спектре клинических ситуаций в детской гематологии. В силу короткого срока хранения КТ технологии инактивации патогенов крайне важны для снижения рисков иммунных реакций и инфекций. Однако существует большое количество исследований, свидетельствующих о том, что функция тромбоцитов при инактивации патогенов может меняться. В обзоре литературы рассмотрены лабораторные и клинические исследования, направленные на оценку значимости и направленности этих изменений, а также обсуждено практическое значение этих исследований для клинической работы с КТ.

Об авторах

Анастасия Александровна Игнатова
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Россия


Павел Евгеньевич Трахтман
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Россия


Михаил Александрович Пантелеев
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Россия


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Для цитирования:


Игнатова А.А., Трахтман П.Е., Пантелеев М.А. Технологии инактивации патогенов и качество концентратов тромбоцитов (обзор литературы). Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2016;15(2):27-31. https://doi.org/10.24287/1726-1708-2016-15-2-27-31

For citation:


Ignatova A.A., Trakhtman P.E., Panteleev M.A. Pathogen inactivation technologies and quality of platelet concentrates (Review of literature). Pediatric Hematology/Oncology and Immunopathology. 2016;15(2):27-31. (In Russ.) https://doi.org/10.24287/1726-1708-2016-15-2-27-31

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)