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Гематологические проявления болезни Гоше (обзор литературы)

https://doi.org/10.24287/1726-1708-2016-15-2-53-58

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Аннотация

Болезнь Гоше - мультисистемное заболевание, развивающееся вследствие дефицита глюкоцереброзидазы и накопления глюкозилцерамида и глюкозилсфингозина в лизосомах фагоцитирующих макрофагов. Представлена характеристика всех типов болезни Гоше. Подробное внимание в обзоре уделяется анализу гематологических проявлений болезни Гоше, приводятся результаты современных исследований, объясняющие их появление при данном заболевании.

Об авторе

Наталия Сергеевна Сметанина
Федеральный научно-клинический центр детской гематологии, онкологии, иммунологии им. Дмитрия Рогачева Минздрава России; Российский национальный исследовательский медицинский университет им. Н.И.Пирогова
Россия


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Для цитирования:


Сметанина Н.С. Гематологические проявления болезни Гоше (обзор литературы). Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2016;15(2):53-58. https://doi.org/10.24287/1726-1708-2016-15-2-53-58

For citation:


Smetanina N.S. Haematologic manifestations of Gaucher’s disease (Review of literature). Pediatric Hematology/Oncology and Immunopathology. 2016;15(2):53-58. (In Russ.) https://doi.org/10.24287/1726-1708-2016-15-2-53-58

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)