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Вопросы гематологии/онкологии и иммунопатологии в педиатрии

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Метастатическое поражение легких при остеосаркоме

Аннотация

Остеосаркома относится к наиболее часто встречающимся злокачественным опухолям костей у детей и подростков. До начала применения полихимиотерапии смертность при метастатической болезни при остеосаркоме находилась на уровне выше 90%.

Несмотря на постоянное развитие протоколов терапии и наблюдения, в процессе лечения у 30-40% пациентов заболевание носит рецидивирующий характер, при этом у более 80% из них выявляются метастазы в легких.

В данном обзоре рассмотрены проблемы диагностики метастатического поражения легких и текущие подходы к методам обнаружения и маркировки метастатических очагов легких малых размеров.

Дополнительной опцией в лечении метастазов легких, недоступных для выявления и хирургической резекции, является проведение интраоперационной изолированной химиоперфузии легкого. Нами были рассмотрены текущие хирургические подходы изолированной перфузии легких.

Об авторе

Илья Владимирович Жилкин
ФГБУ «НМИЦ детской гематологии, онкологии и иммунологии им. Дмитрия Рогачёва» Минздрава России
Россия
к.м.н., врач-педиатр отделения онкологии и детской хирургии


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Жилкин И.В. Метастатическое поражение легких при остеосаркоме. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2019;18(4).

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