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Вопросы гематологии/онкологии и иммунопатологии в педиатрии

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Case report of mesenteric lymphadenopathy in Gaucher disease: rare and benign complication

https://doi.org/10.24287/1726-1708-2021-20-1-168-169

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Аннотация

A 10-year-old boy known case of Gaucher disease about 2 years ago was admitted with nausea, vomiting and epigastric pain from 3 days before hospitalization to Mofid Children’s hospital, Tehran, Iran. On the initial examination, no abnormalities were found except for splenomegaly and brief tenderness on the spleen. In secondary paraclinical evaluations (with Ultrasound and Ct-scan), we noticed mesenteric lymphadenopathy in the patient. The lesions remained unchanged and no significant changes were observed in the clinical and laboratory evaluations of the patient during one-year follow-up period. This is a rare and benign manifestation of Gaucher disease, which is usually monitored and does not require any intervention without signs of malignancy or severe space occupying effects 

Об авторах

M. Khalili
Shahid Beheshti University of Medical Sciences
Иран

Tehran



M. Gholamzadeh Baeis
Shahid Beheshti University of Medical Sciences
Иран

Department of Radiology, Imam Hossein Hospital,

Tehran



M. Alaei
Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences
Россия

Tehran



Список литературы

1. Carubbi F., Cappellini M.D., Fargion S., Fracanzani A.L., Nascimbeni F. Liver involvement in Gaucher disease: A practical review for the hepatologist and the gastroenterologist. Dig Liver Dis 2020; 52 (4): 368–73.

2. Ye Z.-X., Gao X., Qu Q., Ye X., He X.-D. Gaucher Disease with Mesenteric Lymphadenopathy: A Case with 13-year Follow-up. Chin Med J 2016; 129 (20): 2502–3.

3. Simpson E.A., Jaring M.R., Andronikou S. Massive Mesenteric Lymphadenopathy Causing Protein-losing Enteropathy in Gaucher Disease. J Pediatr Hematol Oncol 2017; 39 (5): e300–1.

4. Lee B.H., Kim D.Y., Kim G.H., Cho K.J., Yoon H.K., Yoo H.W. Progressive mesenteric lymphadenopathy with protein-losing enteropathy; a devastating complication in Gaucher disease. Mol Genet Metab 2012; 105 (3): 522–4.

5. Abdelwahab M., SeifEldien H.M. Mesenteric and Mediastinal Lymphadenopathy in Egyptian Children With Gaucher Disease Types 1 and 3 Treated With Enzyme Replacement Therapy. J Pediatr Hematol Oncol 2015; 37 (5): e316– 22.

6. Burrow T.A., Cohen M.B., Bokulic R., Deutsch G., Choudhary A., Falcone R.A. Jr, et al. Gaucher disease: progressive mesenteric and mediastinal lymphadenopathy despite enzyme therapy. J Pediatr 2007; 150 (2): 202–6.

7. Frampas E. Lymphomas: Basic points that radiologists should know. Diagnn Interv Imaging 2013; 94 (2): 131–44.


Для цитирования:


Khalili M., Gholamzadeh Baeis M., Alaei M. Case report of mesenteric lymphadenopathy in Gaucher disease: rare and benign complication. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2021;20(1):168-169. https://doi.org/10.24287/1726-1708-2021-20-1-168-169

For citation:


Khalili M., Gholamzadeh Baeis M., Alaei M. Case report of mesenteric lymphadenopathy in Gaucher disease: rare and benign complication. Pediatric Hematology/Oncology and Immunopathology. 2021;20(1):168-169. (In Russ.) https://doi.org/10.24287/1726-1708-2021-20-1-168-169

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)