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Вопросы гематологии/онкологии и иммунопатологии в педиатрии

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Парентеральная нутритивная поддержка у детей в раннем периоде после трансплантации гемопоэтических стволовых клеток: особенности и клинические аспекты

https://doi.org/10.24287/1726-1708-2021-20-4-199-208

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Аннотация

Трансплантация гемопоэтических стволовых клеток (ТГСК) как метод лечения ассоциирована с нутритивными нарушениями, основные причины которых – нарушения приема пищи и гастроинтестинальные проблемы, развивающиеся на разных этапах: от кондиционирования до позднего посттрансплантационного периода. Нутритивные нарушения негативно влияют на результаты ТГСК, в связи с чем становится ясной актуальность их профилактики и своевременной коррекции. У большинства пациентов, перенесших ТГСК, на различных этапах терапии имеются те или иные проблемы, приводящие к невозможности обеспечения нутритивной потребности энтеральным путем. Поэтому парентеральный путь алиментации у таких пациентов является особенно важным. В обзоре рассмотрены основные клинические особенности назначения парентерального питания пациентам после ТГСК, а также возможные проблемы и негативные последствия его неадекватного назначения. 

Об авторах

А. Ю. Вашура
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России
Россия

заведующий отделом научных основ питания и нутритивно-метаболической терапии ЛРНЦ «Русское поле»,

117997, Москва, ул. Саморы Машела, 1



Ю. А. Алымова
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России
Россия

117997, Москва, ул. Саморы Машела, 1



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Рецензия

Для цитирования:


Вашура А.Ю., Алымова Ю.А. Парентеральная нутритивная поддержка у детей в раннем периоде после трансплантации гемопоэтических стволовых клеток: особенности и клинические аспекты. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2021;20(4):199-208. https://doi.org/10.24287/1726-1708-2021-20-4-199-208

For citation:


Vashura A.Yu., Alymova Yu.A. Parenteral nutritional support in children in the early period after hematopoietic stem cell transplantation: specifics and clinical aspects. Pediatric Hematology/Oncology and Immunopathology. 2021;20(4):199-208. (In Russ.) https://doi.org/10.24287/1726-1708-2021-20-4-199-208

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)