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Лабораторные параметры системы гемостаза у пациентов с COVID-19

https://doi.org/10.24287/1726-1708-2021-20-3-147-155

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Аннотация

Новая коронавирусная инфекция (в настоящее время классифицируемая как COVID-19), впервые выявленная в декабре 2019 г. в Ухане (Китайская Народная Республика), способствовала значительному росту смертности в мире. Помимо дыхательной недостаточности, которую развивают практически все пациенты с COVID-19, распространенным нарушением у них является коагулопатия. В настоящее время COVID-19 продолжает быть жизнеугрожающим заболеванием и требует новых разработок и решений для определения профилактических и лечебных стратегий. В исследованиях часто сообщается об аномалии баланса систем свертывания и фибринолиза при COVID-19, однако до сих пор не существует адекватного набора лабораторных тестов, которые бы смогли обеспечить диагностику коагулопатии при данном заболевании. В настоящем обзоре проведен анализ современных исследований, посвященных клиническим проявлениям коагулопатии при COVID-19, а также проведен анализ информативности лабораторных тестов гемостаза в отношении тяжести течения и клинических исходов при данном заболевании.

Об авторах

Е. А. Серёгина
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России; ФГБУН Центр теоретических проблем физико-химической фармакологии РАН
Россия

Москва



Е. М. Кольцова
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России; ФГБУН Центр теоретических проблем физико-химической фармакологии РАН
Россия

Кольцова Екатерина Михайловна, ведущий научный сотрудник лаборатории трансляционной медицины, заместитель директора по науке–ученый секретарь

117997, Москва, ул. Саморы Машела, 1



Ф. И. Атауллаханов
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России; ФГБУН Центр теоретических проблем физико-химической фармакологии РАН
Россия

Москва



А. Г. Румянцев
ФГБУ «Национальный медицинский исследовательский центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева» Минздрава России
Россия

Москва



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Для цитирования:


Серёгина Е.А., Кольцова Е.М., Атауллаханов Ф.И., Румянцев А.Г. Лабораторные параметры системы гемостаза у пациентов с COVID-19. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2021;20(3):147-155. https://doi.org/10.24287/1726-1708-2021-20-3-147-155

For citation:


Seregina E.A., Koltsova E.M., Ataullakhanov F.I., Rumyantsev A.G. Laboratory parameters of hemostasis in patients with COVID-19. Pediatric Hematology/Oncology and Immunopathology. 2021;20(3):147-155. (In Russ.) https://doi.org/10.24287/1726-1708-2021-20-3-147-155

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)