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Вопросы гематологии/онкологии и иммунопатологии в педиатрии

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ALK-позитивная анапластическая крупноклеточная лимфома: диагностика, клинические проявления, лечение

https://doi.org/10.24287/1726-1708-2015-14-2-12-19

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Аннотация

Анапластические крупноклеточные лимфомы (АККЛ), экспрессирующие киназу анапластической лимфомы (anaplastic lymphoma kinase - ALK), - ALK-позитивные АККЛ - группа злокачественных опухолей лимфоидного происхождения, которые составляют 10-15% от всех неходжкинских лимфом у детей. В обзоре приведены морфологические, фенотипические, цитогенетические и клинические характеристики ALK-позитивной АККЛ, их значение для терапии.

Об авторах

Дмитрий Сергеевич Абрамов
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Россия


Наталья Валерьевна Мякова
Федеральный научно-клинический центр детской гематологии, онкологии и иммунологии им. Дмитрия Рогачева Минздрава России
Россия


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Для цитирования:


Абрамов Д.С., Мякова Н.В. ALK-позитивная анапластическая крупноклеточная лимфома: диагностика, клинические проявления, лечение. Вопросы гематологии/онкологии и иммунопатологии в педиатрии. 2015;14(2):12-19. https://doi.org/10.24287/1726-1708-2015-14-2-12-19

For citation:


Abramov D.S., Myakova N.V. ALK-positive anaplastic large cell lymphoma: Diagnosis, clinical manifestation, therapy. Pediatric Hematology/Oncology and Immunopathology. 2015;14(2):12-19. (In Russ.) https://doi.org/10.24287/1726-1708-2015-14-2-12-19

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ISSN 1726-1708 (Print)
ISSN 2414-9314 (Online)