Aneurysmal bone cyst in children and adolescents
https://doi.org/10.24287/1726-1708-2017-16-2-33-39
Abstract
Aneurysmal bone cyst (ABC) is a destructive, expansive, benign neoplasm of the bone composed of multiloculated blood-filled cystic spaces. ABC is one of the common variant of primary bone lesion in children and adolescents. Using the reproducible clinical settings (age, location in the bone, pattern of bone alteration and type of periosteal reaction) it is not difficult to diagnose this neoplasm except its solid variant. Clinical and histological data were analyzed in order to improve the diagnostic and treatment of children and adolescents with ABC. From January 2009 to October 2016 there were 863 cases of bone tumors in children and adolescents. ABC was found in 58 cases (6,72%). In 13 cases, a pathological bone fracture was the first clinical sign. The correct clinical diagnosis of ABC before histological examination was made only in 22,41% cases. Microscopically, the classic (cystic) variant of ABC was observed in 50 patients, solid variant in 8 cases. The most difficult differential diagnosis of the aneurysmal bone cyst was with the teleangiectatic osteosarcoma, which has many clinical, radiological and histological similarities. ABC should be diagnosed and treated by a multidisciplinary approach by their clinical, radiological, and histological features.
About the Authors
D. V. Rogozhin
Russian Children's Clinical Hospital Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
MD, head of the pathology department
Russia 119571, Moscow, Leninsky prospekt, 117
D. M. Konovalov
Russian Children's Clinical Hospital Ministry of Healthcare of the Russian Federation
National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
N. A. Bolshakov
National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
Russian Federation
A. G. Talalaev
Russian Children's Clinical Hospital Ministry of Healthcare of the Russian Federation
National Scientific and Practical Center of Pediatric Hematology, Oncology and Immunology named after Dmitry Rogachev
Russian Federation
Russian Federation
A. S. Kozlov
Russian Children's Clinical Hospital Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
A. S. Kuzin
Russian Children's Clinical Hospital Ministry of Healthcare of the Russian Federation
Russian Federation
Russian Federation
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Review
For citations:
Rogozhin D.V., Konovalov D.M., Bolshakov N.A., Talalaev A.G., Kozlov A.S., Kuzin A.S. Aneurysmal bone cyst in children and adolescents. Pediatric Hematology/Oncology and Immunopathology. 2017;16(2):33-39. (In Russ.) https://doi.org/10.24287/1726-1708-2017-16-2-33-39
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